Intracellular Amplifier
This is a precision-crafted
microelectrode amplifier designed especially for the exacting
requirements of intracellular neurological studies. It is a
self-contained unit with many built-in features that reduce
the need for additional instrumentation and provides the research
scientist with versatility, accuracy, and ease of operation.
The Digital Panel Meter produces a highly accurate display
of membrane potential, injected current, or electrode resistance.
The internal Dual-Function Transient Control and the DC balance
Control assure extremely precise recordings during current injection
without requiring an external bridge or a differential input
oscilloscope. The ten-turn potentiometers used for the DC Offset,
DC balance, Current Injection, and dual Capacitance Compensation
Controls allow high resolution. An internal square-wave generator
supplies 100Hz current to test electrode resistance and to adjust
capacitance compensation, with the resistance values directly
displayed on the Digital Panel Meter.
The Amplifier's advanced current injection system,
adjustable to 0.1nA resolution, allows external switching of
both internal and external current sources. The total current
from all sources can be displayed on the Digital Panel Meter
prior to injection. This capability allows the user to inject
the exact amount of current desired. Depending upon the
requirements of the experiment, the user can also select
either momentary or continuous injection. The unit has been carefully engineered to eliminate noise that might
adversely affect test results. The user has a choice of either
AC or battery power. The internal battery offers 10 hours of
operation before recharging and isolates the instrument from
power-line frequency interference while the floating ground helps
to eliminate ground-loop noise.
The Amplifier can be used with computer equipment
or a standard chart recorder to generate a permanent record
of injected current and neurological response. It has a direct
input for use as a Digital Volt Meter and is also adaptable as
a general purpose electrometer, with outputs displayed on the
Digital Panel Meter.
Digital panel meter provides for display of membrane potential, injected current, or electrode resistance.
Square-wave generator for electrode test and for adjustment of capacitance compensation
Current injection systems to 0.1nA resolution (1ľA maximum), allowing simultaneous stimulating and recording by a single electrode.
Dual-function transient and DC balance controls Low-Pass and Notch Filters
