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Complete 8/16-Channel Pinch Valves Automated Perfusion System with
programmable timers and channel sequences for precise timing during
manual operation
Specifications: |
Pinch tubing O.D.: | 1/8in.
(1/16in. optional) |
Remote control: | Wireless |
Manifold: | 8-channel,
can be reduced down to 1-channel |
Height: | up to 3ft. adjustable, for gravity driven solution flow |
Solution cylinders: | 60ml
x8 syringes |
Tubing: | 100ft. polyethylene tubing, fits
perfusion manifold directly;
50ft. Tygon tubing, fits provided barbed luer connectors for
syringes |
Fitting: | barbed luer-locks and ferrule-type to connect to solution cylinders
and between Tygon & polyethylene tubing |
Anti-vibration mounting: | a. 1x1 ft. stand,
b. magnetic stand,
c. M8 threaded surfaces |
In the pinch valve a soft tubing is pinched closed by the valve, and opens when
the channel is ON. The results are simple tubing replacement and easy system
cleanup after experiments. Recommended for strong solvents and reagents, and for
hard to wash/clean solutions. Designed for animal physiology and cell research applications. The valves are mounted inside a metal box to
shield your system from electrical noise. The system comes with manifold that
fits to perfusion chambers for cultured cells/tissue
slices, Petri dish and oocytes. Includes soft Tygon,
polyethylene tubing and fitting to connect to pinch tubing. Includes 60ml
syringes/reservoirs. Includes easy disconnect luer fitting for tubing and included syringes.
Compatible with data acquisition and imaging systems, compatible with LabView, MatLab, pClamp, IPlab, PatchMaster, Metamorh, MetaFluor.
A custom automation software is also available upon request. Since valves are inside the metal box and are connected to the controller through shielded
cables, there is no electrical noise during switching.
The included unique flexible stand provides vibration-free
operation and includes both a stand and a
small magnetic base. The magnetic base does not take a lot of space from your
set-up, but allows to position perfusion solutions near your sample.
The post consists of 0.5 in. O.D., 1 foot long aluminum parts and
can be extended to 3 feet high. An 1.5 in. flowerette head screw
will fix the syringes on the post, making a traditional syringe holder. Comes with
60ml syringes, stop-cocks, and fitting. The holder can be also mounted on threaded M8 surfaces.
Sample publications.
Complete 16-Channel Pinch Valves Perfusion System
To form a 16-channel setup, this system includes two sets of the above parts, included with the 8-channel system, which can be operated by the same 16-channel controller.
16-channel valve controller
Both system come with a
16-channel controller. The controller opens valves through
- manual buttons
- wireless remote control
- optically isolated digital or TTL signals generated by a computer or other equipment
- analog signal
- RS232 port (or USB connection) for software control
The controller can operate in
AUTO Memory mode, to
program timers and channels sequences
for precise timing during manual operation;
INHIBIT mode with manual and external controls allows you to
switch all channels OFF at once, if required.
The controller has an
option for valves control by Binary Encoding using only 2-4 digital
inputs, in case if a limited number of digital outputs are available
in your system. The RS232 port allows automation of solution
switching and integration with data acquisition and imaging systems.
ANALOG output can be configured to monitor channel switching
during manual operation.
SET output is used to switch an
outflow unit ON automatically every time perfusion is ON.
RS232 port allows software control by any imaging or data acquisition
setup. Can be upgraded to USB/RS232 adapter.
Specifications (controller): |
Channels: | 16 |
Controls: | optically
isolated digital signals and TTL, Analog input, RS232 software command |
Manual Overdrive: | Manual
touch-pad switches, override electronical inputs |
Remote control: | Wireless |
Auto Memory: | To
program timers and channels sequences for precise timing
during manual operation |
Code mode: | Use only 4 TTL inputs to encode all channels |
Close mode: | Inhibits all outputs to the valves, manual and electronical inputs |
Analog and SET outputs: | To switch outflow units
CFPS-1U and for telegraph
output |
Custom modifications: | Additional features can be added or modified on request |
Dimensions: | 5
x 12 x 9 in. |
Power: | 120/240 VAC |
Click on catalog numbers below to purchase online.
Download PDF manual.
Download PDF catalog.
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Bioscience Tools
ph: 877-853-9755, fax: 866-533-7490
email: info@biosciencetools.com
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PRICES AND OPTIONS |
PS-8H |
$2,995 |
Complete 8-Channel Pinch Valves Perfusion System. Includes programmable 16-channel controller,
pinch valves,
SH-1A syringe holder, manifold, tubing and fitting.
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PS-V8 |
$845 |
Additional pinch valves, set of 8, mounted inside an aluminum box to use with perfusion systems.
For use with PC-16 controller.
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silicon-8
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$195 |
Silicone soft pinch valve tubing 1/8 in.
O.D., 100 feet
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PS-S8
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$95 |
Replacement 60ml syringes (containers) for perfusion systems, set of x8
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PS-16H |
$4,395 |
Complete 16-Channel Pinch Valves Perfusion System. Includes programmable 16-channel controller,
pinch valves,
SH-1A syringe holders, manifold, tubing and fitting.
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Sample publications:
12
A compact microscope for voltage imaging.
Journal of Optics, Volume 24, Number 5, 2022;
45
Sites of Circadian Clock Neuron Plasticity Mediate Sensory Integration and Entrainment.
2021;
44
A compact microscope for voltage imaging.
Journal of Optics, Volume 24, Number 5 2022;
43
Conformational Changes in the 5-HT3A Receptor Extracellular Domain Measured by Voltage Clamp Fluorometry.
Molecular Pharmacology October 3, 2019;
42
Synchronized Retrovirus Fusion in Cells Expressing Alternative Receptor Isoforms Releases the Viral Core into Distinct Sub-cellular Compartments
PLoS Pathogens, Volume 8, Number 5, 2012;
41
Cotransporter-mediated water transport underlying cerebrospinal fluid formation
Nature Communicationsvolume 9, Article number: 2167 (2018);
40
A novel inwardly rectifying K+ channel, Kir2.5, is upregulated under chronic cold stress in fish cardiac myocytes.
Journal of Experimental Biology 2008 211: 2162-2171;
39
Full mutational mapping of titratable residues helps to identify proton-sensors involved in the control of channel gating in the Gloeobacter violaceus pentameric ligand-gated ion channel.
PLOS Biology December 27, 2017;
38
Optical Quantification of Intracellular pH in Drosophila melanogaster Malpighian Tubule Epithelia with a Fluorescent Genetically-encoded pH Indicator.
J. Vis. Exp. (126), e55698, doi:10.3791/55698 (2017);
37
Fusion of Mature HIV-1 Particles Leads to Complete Release of a Gag-GFP-Based Content Marker and Raises the Intraviral pH.
PLoS ONE Volume 8, Number 8 2013;
36
Exocytotic release of ATP by preBötzinger Complex astrocytes contributes to the hypoxic ventilatory response via a calcium-dependent P2Y1 receptor mechanism;
35
Connectivity, Organization, and Network Coordination of the Drosophila Central Circadian Clock;
34
EFFECT OF ECONAZOLE AND BENZYDAMINE ON SENSORY NEURONS IN CULTURE.
JPP No 6/2016 article 06;
33
Independent role for presynaptic FMRP revealed by an FMR1 missense mutation associated with intellectual disability and seizures.
PNAS vol. 112 no. 4, 949–956;
32
Optogenetic Control of Gene Expression in Drosophila.
PLOS one, September 18, 2015;
31
Spatiotemporal Coding of Individual Chemicals by the Gustatory System.
The Journal of Neuroscience, 2 September 2015, 35(35): 12309-12321;
30
Evaluating the Functionality of Conjunctiva Using a Rabbit Dry Eye Model.
Journal of Ophthalmology Volume 2016 (2016);
29
Visualization of retrovirus uptake and delivery into acidic endosomes.
Biochemical Journal Mar 15, 2011, 434 (3) 559-569;
28
Basolateral and central amygdala differentially recruit and maintain dorsolateral striatumdependent cocaine-seeking habits.
NATURE COMMUNICATIONS 14 Dec 2015;
27.
Human sensory neurons: membrane properties and sensitization by inflamatory mediators.
PAIN 155 (2014) 1861-1870;
26.
Size-Dependent Cellular Uptake and Expulsion of Single-Walled Carbon Nanotubes: Single Particle Tracking and a Generic Uptake Model for Nanoparticles.
ACS Nano, 2009, 3 (1), pp 149–158;
25.
Analysis of functional neuronal connectivity in the Drosophila brain.
J Neurophysiol. 2012 Jul 15; 108(2): 684–696;
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10,
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8,
9,
1,
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