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High Performance 16-Channel Miniature Perfusion System
Specifications: |
Response time: | 1.5ms |
Manifold: | two 8-channel, each can be reduced down to 1-channel |
Height: | up to 3ft. adjustable, for gravity driven solution flow |
Pressure: | 15 PSI adjustable, for micro-volume delivery |
Solution cylinders: | 60ml x16 |
Pressure cylinders: | 10ml x8, 50ml x8 |
Gas adapter: | to saturate solutions with gas mixture |
micro-Manifold: | 8-channel, 360, 250 and 100 micron
outflow tips included, Teflon connecting tubing 2ft. per channel |
Small volume delivery system: | 8-channel, Teflon connecting tubing 2ft. per channel, ferrule-type fitting to polyethylene tubing |
Outflow unit: | 22ml/min, provides suction for bath chambers and washout |
Tubing: | 100ft. polyethylene tubing, fits valves and perfusion manifold directly;
50ft. Tygon tubing, fits provided barbed luer-locks |
Fitting: | barbed luer-locks and ferrule-type to connect to solution cylinders
and between Tygon & polyethylene tubing |
Anti-vibration mounting: | a. 1x1 ft. stand,
b. magnetic stand,
c. M8, M6, or 1/4-20 threaded surfaces |
 This system is
used to change solution in the bath around your sample, or to apply
test compounds locally using miniature manifolds. Switch solution valves
are placed in 125mm L x 50mm W x 15mm H aluminum box.
Included 1 ft. and X-blocks attach the valves to the included
vibration-free syringe holder or
to a regular 0.5 in. stand.
This allows you to position valves near the sample over a microscope
stage to minimize the dead volume inside tubing. Comes
with tubing, and manifolds. Includes easy disconnect fitting for tubing and included syringes.
Comes with a
16-channel controller. The
controller opens valves through
- manual buttons
- wireless remote control
- digital or TTL signals generated by a computer or other equipment
- analog signal
- RS232 port (or USB connection) for software control
Compatible with data acquisition and imaging systems.
Includes laptop computer with installed software to generate solution switching sequences to automate complex routine protocols.
Since valves are inside the metal box and are connected to the controller through shielded
cables, there is no electrical noise during switching.
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The included unique syringe holder provides vibration-free
operation and includes both a stand and a
small magnetic base. The magnetic base does not take a lot of space from your
set-up, but allows to position perfusion solutions near your sample.
The post consists of 0.5 in. O.D., 1 foot long aluminum parts and
can be extended to 3 feet high. An 1.5 in. flowerette head screw
will fix the syringes on the post, making a traditional syringe holder. Comes with
60ml syringes, stop-cocks, and fitting. The holder can be also mounted on threaded M6,
M8 or 1/4-20 surfaces.
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Includes Gas Mixture Delivery Adapter
Adapter for syringe holders to connect to a gas source to saturate/bubble
solutions during experiments (CO2 saturation or oxygination, for example.) Comes
with X-block to fit 0.5 in. posts. Includes 9 stop-cocks and plugs to close
unused channels or the common inlet. Includes thin tubing with luer fitting to connect to stop-cocks to form bubbles inside the
solutions. Can be also used to pressurize solutions by connecting to pressure
cylinders PC. Can be connected to another adapter to use the same source of gas
mixture/pressure. Click on image to enlarge.
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Includes Cylinder to pressurize/oxygenate solutions, set of 16 (10ml x 8 and 50ml x 8)
A set of autoclavable cylinders to pressurize your solutions. Can be used to
drive solutions through 100 micron tip of MM manifold, for example. Can be also
used to saturate solutions with gases (bubbling) by feeding a thin tubing inside
the cylinder, or to degas solutions by applying vacuum. Can be used with syringe
heaters SYR-T8. Comes with stop-cocks and fitting for 1/16 in. I.D. tubing.
Includes 3-way valves to connect to a pressure source, to release the pressure,
to refill the cylinder, or to connect to a source of gas mixture (oxigenation,
for example). Comes with threaded covers for easy refill. Material:
polypropylene. Large (up to 650ml) volumes are available
upon request. Cylinders with built-in 10, 25 or 40 micron filters are also
available. Volumes up to 100ml fit inside SH-1A syringe
holders. Click on image to enlarge.
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Includes pressurized Small Volume Delivery System SVDS1
For use with lab-on-chips, intracellular
perfusion and small chambers. Solutions are either
withdrawn using controlled flow systems or pushed
by pressure.
The majority of available perfusion systems have long lines
of tubing, which have to be filled before conducting experiments. However,
sometimes applied substances are available only in limited quantities or are
extremely expensive, prohibiting the usage of conventional perfusion systems.
This system utilizes small plastic tubes with conical bottom and thin Teflon
tubing to connect to your system. It can be used with as little as 100 µl
volumes of solution. Tubes with solutions are simply threaded into the holder.
Solutions are easy to refill during the experiment. Can be used with miniature
manifolds. Uses pressure source built-inside
the controller to
deliver the solutions, unless the solutions are withdrawn by a negative pressure
like in controlled flow system or
intracellular perfusion setup. The system comes
with all necessary tubing and fitting to connect to a single pressure source. The small size of 91 x 48 x 17 mm (without tubing attached) allows to
position solutions near your sample. Can be attached to a 1 ft. rod (included).
Comes with X-block to attach onto a standard 0.5 in. stand. The body has 6.5 mm
I.D. opening, which allows to mount the system on a micromanipulator. Includes
16 plastic replaceable tubes (2 and 3.5ml). Click on image to enlarge.
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Includes Miniature Manifold for Single Cell Superfusion
Miniature manifolds are used to achieve fast solution application to small
samples (single cells, for example). Due to the small size of the sample,
solution exchange around the sample can happen in as fast as few ms. The
miniature manifolds also offer advantage of not contaminating the whole bath
chamber, but applying the substances locally (provided that
perfusion chamber is used with frequent wash). Comes
with three replaceable threaded tips of 360, 250 and 100 micron I.D.
Incorporates 2 ft. long Teflon tubing for direct connection to perfusion
systems. Inside tubing is easy to wash. The threaded replaceable tips are
washable and allow one to use the manifold with solutions under higher pressure.
The length of tips is around 1 in., which can be cut to the required length.
Incorporates 10cm long 4mm O.D. rod to mount on miniature manipulators and 7mm
O.D. adapter to mount on regular
manipulators. Incorporates eight separate channels. If used with less number of solutions, multiple channels are filled
with the same solution, which accelerates washout and delivery.
Includes two nozzles to use with small volume chambers as a regular manifold
(the rod fits inside magnetic holders MTH). Click on
image to enlarge.
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Includes Flow Control Unit, 30µl/min to 22 ml/min
Comes with a set of tubing for different flow ranges up to 22 ml/min. Includes a DC power supply.
This high flow rate unit can be used for solution
suction/aspiration from open perfusion chambers. The unit is configured as an analog option for automatic outflow when perfusion is turned ON.
Click on image to enlarge.
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16-channel valve controller
 The included 16-channel controller can operate in
AUTO Memory mode, when a set of
chosen valves opens automatically at the time the other valves
close. This is useful for automatic switching to preset solutions
after the test solution is OFF, and provides uninterrupted solution
flow.
INHIBIT mode with manual and external controls allows you to
switch all channels OFF at once, if required.
The controller has an
option for valves control by Binary Encoding using only 2-4 digital
inputs, in case if a limited number of digital outputs are available
in your system. The RS232 port allows automation of solution
switching and integration with imaging
systems.
ANALOG output can be configured to monitor channel switching
during manual operation. By default, ANALOG output is used to switch an
outflow unit ON automatically every time perfusion is ON.
With optional RS232UP upgrade up to 32 channels (two controllers)
can be operated through a single RS232 port. Up to 10 controllers
(RS232UP only) can be connected in a chain to control 320 channels
through the same RS232 (or USB) port.
Comes with an external 120/220V power supply.
Click on image to enlarge.
Click on catalog numbers below to purchase online.
Download PDF manual.
Download PDF catalog.
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Bioscience Tools
ph: 1-877-853-9755
ph: 1-858-537-1062 (from outside USA)
fax: 1-619-582-0919
email: info@biosciencetools.com
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PRICES AND OPTIONS
Perfusion
Systems |
PS15-16E |
$7,995 |
High Performance 16-Channel Fast Miniature Perfusion System. |
PS15-4 |
$1,615 |
Complete 4-Channel Fast Miniature Perfusion System
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PS-8H |
$2,045 |
Complete 8-Channel Pinch Valves Perfusion System. Includes basic 16-channel controller,
pinch valves,
SH-1A syringe holder, manifold, tubing and fitting.
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PS15-8 |
$2,400 |
Complete 8-Channel Fast Miniature Perfusion System. Includes basic 16-channel controller, fast 1.5ms valves,
SH-1A syringe holder, manifold, tubing and fitting. |
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